EPIDERMAL GROWTH-FACTOR STIMULATES PROLIFERATION OF RAT HEPATOMA-CELLS PRODUCING ALPHA-FETOPROTEIN

被引：15

作者：

KANEKO, Y ^{[1
]}

IMAI, Y ^{[1
]}

MATSUZAKI, F ^{[1
]}

ENDO, Y ^{[1
]}

ODA, T ^{[1
]}

机构：

[1] UNIV TOKYO, DEPT MED 3, BUNKYO KU, TOKYO 113, JAPAN

来源：

EXPERIENTIA | 1979年 / 35卷 / 12期

关键词：

D O I：

10.1007/BF01953254

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Epidermal growth factor stimulated both [3H]thymidine uptake and proliferation of rat AH66 hepatoma cells. However, the increase in cell number was not accompanied by a proportional increase in the levels of α-fetoprotein of the culture media. The effects of EGF on the cell proliferation were antagonized by N6, O2′-dibutyryl cAMP. © 1979 Birkhäuser Verlag.

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页码：1660 / 1661

页数：2

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