METERGOLINE ABOLISHES THE PROLACTIN RESPONSE TO BUSPIRONE

被引：17

作者：

GREGORY, CA ^{[1
]}

ANDERSON, IM ^{[1
]}

COWEN, PJ ^{[1
]}

机构：

[1] UNIV OXFORD,LITTLEMORE HOSP,DEPT PSYCHIAT,OXFORD OX4 4XN,ENGLAND

来源：

PSYCHOPHARMACOLOGY | 1990年 / 100卷 / 02期

基金：

英国惠康基金;

关键词：

5-HT; Buspirone; Metergoline; Prolactin;

D O I：

10.1007/BF02244420

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Pretreatment of nine healthy subjects with the non-selective 5-HT receptor antagonist, metergoline (4 mg), abolished the increase in plasma prolactin produced by the anxiolytic drug, buspirone (15 mg). While these findings are consistent with a role for 5-HT receptors in the stimulatory effect of buspirone on plasma prolactin, a dopaminergic mechanism cannot be excluded by the present data. © 1990 Springer-Verlag.

引用

页码：283 / 284

页数：2

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