LATE RECURRENT CANDIDA ENDOCARDITIS

被引：43

作者：

JOHNSTON, PG

LEE, J

DOMANSKI, M

DRESSLER, F

TUCKER, E

ROTHENBERG, M

CUNNION, RE

PIZZO, PA

WALSH, TJ

机构：

[1] NIH,CTR CLIN,DEPT CLIN CARE MED,BLDG 10,RM 13N240,BETHESDA,MD 20892

[2] NCI,DEPT CARDIOL,MED BRANCH,BETHESDA,MD 20892

[3] NCI,DEPT CARDIOL,PATHOL BRANCH,BETHESDA,MD 20892

[4] NCI,DEPT CARDIOL,PEDIAT BRANCH,BETHESDA,MD 20892

来源：

CHEST | 1991年 / 99卷 / 06期

关键词：

D O I：

10.1378/chest.99.6.1531

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Late recurrent Candida endocarditis (LRCE) developed on a prosthetic mitral valve 22 months after treatment for primary native mitral valve endocarditis. The LRCE was difficult to diagnose; results of two dimensional echocardiography and repeated blood cultures were negative. Only transesophageal echocardiography revealed a vegetation and only lysis centrifugation blood cultures demonstrated candidemia. Postmortem examination revealed a large Candida vegetation on the prosthetic valve and Candida in the mitral valve ring. This case and a review of the literature indicate that Candida endocarditis treated with amphotericin B and prosthetic valve replacement may recur months after treatment, and that LRCE, which is difficult to diagnose and treat, may be best prevented by lifelong antifungal suppressive therapy.

引用

页码：1531 / 1533

页数：3

共 17 条

[1] CLINICAL-EVALUATION OF THE LYSIS-CENTRIFUGATION BLOOD CULTURE SYSTEM FOR THE DETECTION OF FUNGEMIA AND COMPARISON WITH A CONVENTIONAL BIPHASIC BROTH BLOOD CULTURE SYSTEM [J].