OXIDATIVE FORMYLATION AND CHLOROMETHYLATION IN VILSMEIER REACTIONS OF O-HETEROCYCLIC AND S-HETEROCYCLIC KETONES

被引：17

作者：

GILES, PR ^{[1
]}

MARSON, CM ^{[1
]}

机构：

[1] UNIV SHEFFIELD,DEPT CHEM,SHEFFIELD S3 7HF,S YORKSHIRE,ENGLAND

来源：

TETRAHEDRON | 1991年 / 47卷 / 07期

关键词：

D O I：

10.1016/S0040-4020(01)86387-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The action of DMF-POCl3 at 20-degrees-C on tetrahydro-4H-pyran-4-one, and thiochroman-4-oen affords the corresponding beta-chllorovinylaldehydes. However, with excess DMF-POCI3 at 100-degrees-C, chroman-4-one affords 3-(chloromethyl)chromone, and thiochromanone gives 3-formylthiochromone. Mechanistics rationalisations are provided.

引用

页码：1303 / 1310

页数：8

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