SALIVARY THC FOLLOWING CANNABIS SMOKING CORRELATES WITH SUBJECTIVE INTOXICATION AND HEART-RATE

被引:49
作者
MENKES, DB
HOWARD, RC
SPEARS, GFS
CAIRNS, ER
机构
[1] UNIV OTAGO,DEPT SOCIAL & PREVENT MED,OTAGO,NEW ZEALAND
[2] UNIV OTAGO,CTR NEUROSCI,OTAGO,NEW ZEALAND
[3] DSIR,DIV CHEM,PETONE,NEW ZEALAND
关键词
HUMAN; CANNABIS; THC; SALIVA; INTOXICATION;
D O I
10.1007/BF02244217
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A cannabis smoking trial was conducted using paid volunteers. Subjective intoxication, measured using a visual analogue scale, was compared with heart rate and with salivary delta-9-tetrahydrocannabinol (THC) levels at various times after smoking a cigarette containing 11 mg THC. Subjective intoxication and heart rate elevation were significantly correlated with the log of salivary THC. Salivary THC levels are a sensitive index of recent cannabis smoking, and appear more closely linked with the effects of intoxication than do either blood or urine cannabinoid levels.
引用
收藏
页码:277 / 279
页数:3
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