ELECTROPHILIC F-18 FROM A SIEMENS 11-MEV PROTON-ONLY CYCLOTRON

被引：25

作者：

CHIRAKAL, R ^{[1
]}

ADAMS, RM ^{[1
]}

FIRNAU, G ^{[1
]}

SCHROBILGEN, GJ ^{[1
]}

COATES, G ^{[1
]}

GARNETT, ES ^{[1
]}

机构：

[1] MCMASTER UNIV,DEPT CHEM,HAMILTON,ON L8S 4M1,CANADA

来源：

NUCLEAR MEDICINE AND BIOLOGY | 1995年 / 22卷 / 01期

关键词：

D O I：

10.1016/0969-8051(94)E0064-P

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Because more and more PET centres are using small proton cyclotrons there is a renewed interest in methods for the production of electrophilic F-18 by proton irradiation of [O-18]O-2. A method for the routine production of clinically useful quantities of [F-18]F-2 having a specific activity of 35 Ci/mmol has been developed and implemented using an 11 MeV proton cyclotron and [O-18]O-2. Based on the yield, purity, reproducibility, and specific activity of [F-18]F-2 this is the most efficient method reported thus far.

引用

页码：111 / 116

页数：6

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