SYNTHESIS OF THE TETRAHYDROFURAN RING PART OF A MARINE TOXIN POLYCAVERNOSIDE-A

被引：19

作者：

HAYASHI, N ^{[1
]}

MINE, T ^{[1
]}

FUJIWARA, K ^{[1
]}

MURAI, A ^{[1
]}

机构：

[1] HOKKAIDO UNIV, FAC SCI, DEPT CHEM, SAPPORO, HOKKAIDO 060, JAPAN

来源：

CHEMISTRY LETTERS | 1994年 / 11期

关键词：

D O I：

10.1246/cl.1994.2143

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Construction of the tetrahydrofuran ring part of polycavernoside A, which has been isolated as one of toxic principles from the red alga Polycavernosa tsudai, is described starting from 2,2-dimethylpropane-1,3-diol. The synthesis involves the Sharpless epoxidation and the Evans procedure for introduction of three chiral centers.

引用

页码：2143 / 2146

页数：4

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