ENHANCED INGROWTH OF POROUS-COATED COCR IMPLANTS PLASMA-SPRAYED WITH TRICALCIUM PHOSPHATE

被引:41
作者
CHAE, JC [1 ]
COLLIER, JP [1 ]
MAYOR, MB [1 ]
SURPRENANT, VA [1 ]
DAUPHINAIS, LA [1 ]
机构
[1] DARTMOUTH COLL, DEPT BIOMED ENGN, HANOVER, NH 03756 USA
来源
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1992年 / 26卷 / 01期
关键词
D O I
10.1002/jbm.820260109
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Tricalcium phosphate (TCP) is an osteoconductive bioceramic which, when applied to a porous-coated prosthesis, may enhance osseous ingrowth and mechanical stability. TCP plasma-sprayed and unsprayed porous-coated tibial intramedullary rods were bilaterally implanted in seven adult rabbits. All rabbits were killed at 12 weeks. Pull-out tests were performed on 4 rabbits while all were evaluated histologically for osseous response and adverse tissue reaction. TCP-sprayed implants showed significantly greater osseous ingrowth in comparison to unsprayed implants. Neither implant type exhibited adverse tissue reactions. Average pull-out strengths were 69 lb for treated rods and 72 lb for controls (p > 0.05); quality of fit for all pull-out specimens except one was deemed poor. We conclude that plasma-sprayed TCP enhances osseous ingrowth into porous-coated devices. However, our data further suggest that enhanced ingrowth may not always lead to enhanced fixation.
引用
收藏
页码:93 / 102
页数:10
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