NARROW-BAND (TL-01) UVB AIR-CONDITIONED PHOTOTHERAPY FOR CHRONIC SEVERE ADULT ATOPIC-DERMATITIS

被引:116
作者
GEORGE, SA
BILSLAND, DJ
JOHNSON, BE
FERGUSON, J
机构
[1] Photobiology Unit, Department of Dermatology, Ninewells Hospital and Med. School
关键词
D O I
10.1111/j.1365-2133.1993.tb00147.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
In an open study of 21 severely affected adult atopic dermatitis patients, air-conditioned narrow-band UVB phototherapy using the Philips TL-01 lamp three times weekly for 12 weeks resulted in a 68% reduction in atopic dermatitis severity scores, with a concomitant 88% reduction in potent topical steroid use. Follow-up at 24 weeks revealed that six patients had relapsed to > 70% of pre-phototherapy severity scores; the remaining 15 continued to derive long-term benefit. The mean value of potent topical steroid use remained 50% below pre-phototherapy needs. Narrow-band UVB (TL-01) phototherapy appears an effective, steroid-sparing treatment for chronic severe atopic dermatitis, offering long-term benefits in the majority of those treated.
引用
收藏
页码:49 / 56
页数:8
相关论文
共 43 条
  • [1] THE ROLE OF PSORALEN PHOTOCHEMOTHERAPY (PUVA) IN THE TREATMENT OF SEVERE ATOPIC ECZEMA IN ADOLESCENTS
    ATHERTON, DJ
    CARABOTT, F
    GLOVER, MT
    HAWK, JLM
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1988, 118 (06) : 791 - 795
  • [2] BINET O, 1982, ANN DERMATOL VENER, V109, P589
  • [3] COSTA C, 1989, ACTA DERM-VENEREOL, V69, P41
  • [4] AN APPRAISAL OF ULTRAVIOLET LAMPS USED FOR THE PHOTOTHERAPY OF PSORIASIS
    DIFFEY, BL
    FARR, PM
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1987, 117 (01) : 49 - 56
  • [5] FALK ES, 1985, PHOTODERMATOLOGY, V2, P241
  • [6] FISCHER T, 1976, ACTA DERM-VENEREOL, V56, P473
  • [7] FLINDTHANSEN H, 1991, ACTA DERM-VENEREOL, V71, P245
  • [8] LONG-TERM FOLLOW-UP OF SKIN-CANCER IN THE PUVA-48 COOPERATIVE STUDY
    FORMAN, AB
    ROENIGK, HH
    CARO, WA
    MAGID, ML
    [J]. ARCHIVES OF DERMATOLOGY, 1989, 125 (04) : 515 - 519
  • [9] GOLDBERG HC, 1980, ACTA DERM-VENEREOL, V92, P119
  • [10] 3II-NM UVB PHOTOTHERAPY - AN EFFECTIVE TREATMENT FOR PSORIASIS
    GREEN, C
    FERGUSON, J
    LAKSHMIPATHI, T
    JOHNSON, BE
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1988, 119 (06) : 691 - 696