SPROUTING OF PERIPHERAL-NERVE AXONS IN THE SPINAL-CORD OF MONKEYS

被引：46

作者：

FLORENCE, SL ^{[1
]}

GARRAGHTY, PE ^{[1
]}

CARLSON, M ^{[1
]}

KAAS, JH ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DEPT NEUROBIOL,BOSTON,MA 02115

来源：

BRAIN RESEARCH | 1993年 / 601卷 / 1-2期

关键词：

REGENERATION; PLASTICITY; DORSAL HORN; DORSAL COLUMN NUCLEUS; CUNEATE NUCLEUS; PRIMATE;

D O I：

10.1016/0006-8993(93)91734-A

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

It has been previously suggested that two conditions must be met in order for sprouting to occur in the dorsal horn of the spinal cord: afferent fibers must be stimulated to grow and alternate synaptic sites must be made available. We show that reversibly deactivating peripheral nerve axons by nerve crush alone, which produces little or no additional available synaptic sites, results in expansion of the peripheral nerve inputs in the spinal cord in both adult and infant macaque monkeys.

引用

页码：343 / 348

页数：6

共 36 条

[1] REORGANIZATION OF SOMATOSENSORY AREA 3B REPRESENTATIONS IN ADULT OWL MONKEYS AFTER DIGITAL SYNDACTYLY
ALLARD, T
CLARK, SA
JENKINS, WM
MERZENICH, MM
[J]. JOURNAL OF NEUROPHYSIOLOGY, 1991, 66 (03) : 1048 - 1058
[2] A PHYSIOLOGICAL-BASIS FOR A THEORY OF SYNAPSE MODIFICATION
BEAR, MF
COOPER, LN
EBNER, FF
[J]. SCIENCE, 1987, 237 (4810) : 42 - 48
[3] A MEMBRANE PHOSPHOPROTEIN ASSOCIATED WITH NEURAL DEVELOPMENT, AXONAL REGENERATION, PHOSPHOLIPID-METABOLISM, AND SYNAPTIC PLASTICITY
BENOWITZ, LI
ROUTTENBERG, A
[J]. TRENDS IN NEUROSCIENCES, 1987, 10 (12) : 527 - 532
[4] EVIDENCE THAT FINE PRIMARY AFFERENT AXONS INNERVATE A WIDER TERRITORY IN THE SUPERFICIAL DORSAL HORN FOLLOWING PERIPHERAL AXOTOMY
CAMERON, AA
POVER, CM
WILLIS, WD
COGGESHALL, RE
[J]. BRAIN RESEARCH, 1992, 575 (01) : 151 - 154
[5] COTMAN CW, 1985, SYNAPTIC PLAST
[6] Darian-Smith, 1984, HDB PHYSL 2 1, V3, P789
[7] COLLATERAL SPROUTING OF THE CENTRAL TERMINALS OF CUTANEOUS PRIMARY AFFERENT NEURONS IN THE RAT SPINAL-CORD - PATTERN, MORPHOLOGY, AND INFLUENCE OF TARGETS
FITZGERALD, M
WOOLF, CJ
SHORTLAND, P
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1990, 300 (03) : 370 - 385
[8] FLORENCE S L, 1988, Society for Neuroscience Abstracts, V14, P475
[9] SOMATOTOPIC ORGANIZATION OF INPUTS FROM THE HAND TO THE SPINAL GRAY AND CUNEATE NUCLEUS OF MONKEYS WITH OBSERVATIONS ON THE CUNEATE NUCLEUS OF HUMANS
FLORENCE, SL
WALL, JT
KAAS, JH
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1989, 286 (01) : 48 - 70
[10] CENTRAL PROJECTIONS FROM THE SKIN OF THE HAND IN SQUIRREL-MONKEYS
FLORENCE, SL
WALL, JT
KAAS, JH
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1991, 311 (04) : 563 - 578

← 1 2 3 4 →