THE GENE FOR THE AMYLOID PRECURSOR-LIKE PROTEIN-APLP2 IS ASSIGNED TO HUMAN CHROMOSOME-11Q23-Q25

被引：21

作者：

VONDERKAMMER, H

LOFFLER, C

HANES, J

KLAUDINY, J

SCHEIT, KH

HANSMANN, I

机构：

[1] MAX PLANCK INST BIOPHYS CHEM,MOLEK BIOL ABT,FASSBERG,D-37077 GOTTINGEN,GERMANY

[2] UNIV GOTTINGEN,INST HUMANGENET,D-37073 GOTTINGEN,GERMANY

来源：

GENOMICS | 1994年 / 20卷 / 02期

关键词：

D O I：

10.1006/geno.1994.1174

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The human amyloid precursor-like protein APLP2 is a highly conserved homologue of a sequence-specific DNA-binding mouse protein with a predicted function in the cell cycle. Somatic cell hybrids segregating human chromosomes were used to assign the APLP2 gene to chromosome 11. Fluorescence in situ hybridization confirmed this assignment and further localized the gene to q23-q25. (C) 1994 Academic Press, Inc.

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页码：308 / 311

页数：4

相关论文

共 21 条

[1] RECOGNITION OF THE CDEI MOTIF GTCACATG BY MOUSE NUCLEAR PROTEINS AND INTERFERENCE WITH THE EARLY DEVELOPMENT OF THE MOUSE EMBRYO [J].

BLANGY, A ;

LEOPOLD, P ;

VIDAL, F ;

RASSOULZADEGAN, M ;

CUZIN, F .

NUCLEIC ACIDS RESEARCH, 1991, 19 (25) :7243-7250

[2] NIGMS HUMAN RODENT SOMATIC-CELL HYBRID MAPPING PANEL-1 AND PANEL-2 [J].

DRWINGA, HL ;

TOJI, LH ;

KIM, CH ;

GREENE, AE ;

MULIVOR, RA .

GENOMICS, 1993, 16 (02) :311-314

[3]

FRYNS JP, 1986, CLIN GENET, V30, P255

[4] CHARACTERIZATION AND CHROMOSOMAL LOCALIZATION OF A CDNA-ENCODING BRAIN AMYLOID OF ALZHEIMERS-DISEASE [J].

GOLDGABER, D ;

LERMAN, MI ;

MCBRIDE, OW ;

SAFFIOTTI, U ;

GAJDUSEK, DC .

SCIENCE, 1987, 235 (4791) :877-880

[5] THE COMPLETE CDNA CODING SEQUENCE FOR THE MOUSE CDEI BINDING-PROTEIN [J].

HANES, J ;

VONDERKAMMER, H ;

KRISTJANSSON, GI ;

SCHEIT, KH .

BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1216 (01) :154-156

[6] THE PRECURSOR OF ALZHEIMERS-DISEASE AMYLOID-A4 PROTEIN RESEMBLES A CELL-SURFACE RECEPTOR [J].

KANG, J ;

LEMAIRE, HG ;

UNTERBECK, A ;

SALBAUM, JM ;

MASTERS, CL ;

GRZESCHIK, KH ;

MULTHAUP, G ;

BEYREUTHER, K ;

MULLERHILL, B .

NATURE, 1987, 325 (6106) :733-736

[7] DELINEATION OF INDIVIDUAL HUMAN-CHROMOSOMES IN METAPHASE AND INTERPHASE CELLS BY INSITU SUPPRESSION HYBRIDIZATION USING RECOMBINANT DNA LIBRARIES [J].

LICHTER, P ;

CREMER, T ;

BORDEN, J ;

MANUELIDIS, L ;

WARD, DC .

HUMAN GENETICS, 1988, 80 (03) :224-234

[8] HIGH-RESOLUTION MAPPING OF HUMAN CHROMOSOME-11 BY INSITU HYBRIDIZATION WITH COSMID CLONES [J].

LICHTER, P ;

TANG, CJC ;

CALL, K ;

HERMANSON, G ;

EVANS, GA ;

HOUSMAN, D ;

WARD, DC .

SCIENCE, 1990, 247 (4938) :64-69

[9]

MCKUSICK VA, 1992, MENDELIAN INHERITANC, P630

[10] SPLICING OF MESSENGER-RNA PRECURSORS [J].

PADGETT, RA ;

GRABOWSKI, PJ ;

KONARSKA, MM ;

SEILER, S ;

SHARP, PA .

ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :1119-1150