HEMOCOMPATIBLE PROPERTIES OF POLYMERIC DERIVATIVE OF PARACETAMOL

被引：22

作者：

DEQUEIROZ, AAA

GALLARDO, A

ROMAN, JS

HIGA, OZ

机构：

[1] CSIC, INST CIENCIA & TECNOL POLIMEROS, MADRID, SPAIN

[2] IPEN CNEN SP, SAO PAULO, BRAZIL

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 1995年 / 7卷 / 06期

关键词：

ANTITHROMBOGENIC; PROTEINS; COMPOSITIONS; HYDROGEL; COPOLYMER COMPOSITION;

D O I：

10.1163/156856295X00580

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Copolymerization of N,N-dimethylacrylamide (DMAA) and p-acryloyloxiacetanilide (AOA) was carried out at different mole ratios of the monomers to obtain copolymers of varying compositions. DMAA contents were very near to the corresponding monomer feed and varied between 0.20 and 0.80. Investigation of the protein adsorption of these polymer surfaces showed that copolymers with higher DMAA content adsorbed more albumin than fibrinogen. The scanning electron micrographs of the polymer-coated coverslips after contact with blood showed an antithrombogenic behaviour of these surfaces.

引用

页码：523 / 530

页数：8

共 28 条

[1] STUDY ON THE PREVENTION OF SURFACE-INDUCED PLATELET ACTIVATION BY ALBUMIN COATING [J].