ANIMAL-MODELS OF PROTECTIVE IMMUNITY IN TUBERCULOSIS TO EVALUATE CANDIDATE VACCINES

被引：48

作者：

GRIFFIN, JFT

MACKINTOSH, CG

BUCHAN, GS

机构：

[1] UNIV OTAGO, DEPT MICROBIOL, DEER RES LAB, DUNEDIN, NEW ZEALAND

[2] AGRES, INVERMAY AGR RES CTR, DEER RES UNIT, MOSGIEL, NEW ZEALAND

来源：

TRENDS IN MICROBIOLOGY | 1995年 / 3卷 / 11期

关键词：

D O I：

10.1016/S0966-842X(00)88994-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

While the etiology of tuberculosis is well understood, the nature of the protective immune response to the causative mycobacteria has remained a mystery. There is an urgent need to define protective immunity critically, and to develop alternative animal models to evaluate the efficacy of new-generation vaccines against tuberculosis in a cost-effective way.

引用

页码：418 / 424

页数：7

共 50 条

[1] EFFECTIVE VACCINATION OF MICE AGAINST MYCOBACTERIUM-TUBERCULOSIS INFECTION WITH A SOLUBLE MIXTURE OF SECRETED MYCOBACTERIAL PROTEINS
ANDERSEN, P
[J]. INFECTION AND IMMUNITY, 1994, 62 (06) : 2536 - 2544
[2] BEATSON NS, 1985, ROYAL SOC NZ B, V22, P147
[3] TUBERCULOSIS - COMMENTARY ON A REEMERGENT KILLER
BLOOM, BR
MURRAY, CJL
[J]. SCIENCE, 1992, 257 (5073) : 1055 - 1064
[4] HUMAN MYCOBACTERIUM-TUBERCULOSIS-REACTIVE CD4+ T-CELL CLONES - HETEROGENEITY IN ANTIGEN RECOGNITION, CYTOKINE PRODUCTION, AND CYTOTOXICITY FOR MONONUCLEAR PHAGOCYTES
BOOM, WH
WALLIS, RS
CHERVENAK, KA
[J]. INFECTION AND IMMUNITY, 1991, 59 (08) : 2737 - 2743
[5] A STRATEGY TO IMPROVE THE EFFICACY OF VACCINATION AGAINST TUBERCULOSIS AND LEPROSY
BRETSCHER, PA
[J]. IMMUNOLOGY TODAY, 1992, 13 (09): : 342 - 345
[6] IDENTIFICATION OF HETEROLOGOUS MONOCLONAL-ANTIBODIES THAT CROSS-REACT WITH CERVINE LEUKOCYTE SUBPOPULATIONS
BUCHAN, GS
GRIFFIN, JFT
[J]. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1990, 24 (03) : 247 - 257
[7] TUBERCULOSIS IN DOMESTICATED DEER (CERVUS-ELAPHUS) - A LARGE ANIMAL-MODEL FOR HUMAN TUBERCULOSIS
BUCHAN, GS
GRIFFIN, JFT
[J]. JOURNAL OF COMPARATIVE PATHOLOGY, 1990, 103 (01) : 11 - 22
[8] EXPERIMENTAL MYCOBACTERIUM-BOVIS INFECTION OF CATTLE - EFFECT OF DOSE OF M-BOVIS AND PREGNANCY ON IMMUNE-RESPONSES AND DISTRIBUTION OF LESIONS
BUDDLE, BM
ALDWELL, FE
PFEFFER, A
DELISLE, GW
CORNER, LA
[J]. NEW ZEALAND VETERINARY JOURNAL, 1994, 42 (05) : 167 - 172
[9] EFFECTS OF NITRIC-OXIDE SYNTHASE INHIBITORS ON MURINE INFECTION WITH MYCOBACTERIUM-TUBERCULOSIS
CHAN, J
TANAKA, K
CARROLL, D
FLYNN, J
BLOOM, BR
[J]. INFECTION AND IMMUNITY, 1995, 63 (02) : 736 - 740
[10] DIAGNOSIS AND EPIDEMIOLOGY OF BOVINE TUBERCULOSIS USING MOLECULAR BIOLOGICAL APPROACHES
COLLINS, DM
RADFORD, AJ
DELISLE, GW
BILLMANJACOBE, H
[J]. VETERINARY MICROBIOLOGY, 1994, 40 (1-2) : 83 - 94

← 1 2 3 4 5 →