ALPHA-MELANOCYTE-STIMULATING HORMONE - REDUCTION IN ADULT-RAT BRAIN AFTER MONOSODIUM GLUTAMATE TREATMENT OF NEONATES

被引：68

作者：

ESKAY, RL

BROWNSTEIN, MJ

LONG, RT

机构：

[1] Laboratory of Clinical Science, National Institute of Mental Health, Bethesda

来源：

SCIENCE | 1979年 / 205卷 / 4408期

关键词：

D O I：

10.1126/science.462194

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Intraperitoneal injection of monosodium glutamate in neonatal rats resulted in a 90 percent loss of α-melanocyte-stimulating hormone in hypothalamic and extrahypothalamic areas of the brain, whereas the amount of hormone in the pituitary gland did not change. The dramatic reduction of α-melanocyte- stimulating hormone in the brain suggests that its primary source there is the neuronal perikarya of the arcuate nucleus. Copyright © 1979 AAAS.

引用

页码：827 / 829

页数：3

共 69 条

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