RETENTION INDEX SCALE FOR LIQUID-LIQUID CHROMATOGRAPHY

被引:129
作者
BAKER, JK
MA, CY
机构
[1] Department of Medicinal Chemistry, School of Pharmacy, University of Mississippi, University
来源
JOURNAL OF CHROMATOGRAPHY | 1979年 / 169卷 / FEB期
关键词
D O I
10.1016/0021-9673(75)85036-9
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A retention index scale based on the relative retention of a homologous series of C3 C23 2-keto alkanes was used to characterize the chromatographic properties of several drugs with four basic reversed-phase systems each using several mobile phase compositions. The retention index of a given drug was found to be fairly independent of exact composition of the mobile phase. Small changes in the retention index were observed for some drugs following a change in column type and these index changes could be related to changes in selectivity of the solvent-column system. © 1979.
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页码:107 / 115
页数:9
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