BRIDGING NERVE DEFECTS WITH COMBINED SKELETAL-MUSCLE AND VEIN CONDUITS

被引：119

作者：

BRUNELLI, GA ^{[1
]}

BATTISTON, B ^{[1
]}

VIGASIO, A ^{[1
]}

BRUNELLI, G ^{[1
]}

MAROCOLO, D ^{[1
]}

机构：

[1] UNIV BRESCIA,ORTOPED CLIN,SEZ MICROCHURURG,BRESCIA,ITALY

来源：

MICROSURGERY | 1993年 / 14卷 / 04期

关键词：

D O I：

10.1002/micr.1920140407

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The use of vein or muscle grafts to bridge nerve defects longer than 1-1.5 cm gives poor results. Veins collapse and in muscle grafts axons may regrow outside the graft. We used veins (to guide regeneration) filled with muscle (to avoid vein collapse). Nerve regeneration through 1 and 2 cm grafts made of vein plus muscle was compared with similarly long traditional nerve grafts, free fresh muscle grafts, and empty vein grafts. Regeneration was assessed clinically and histologically (qualitative and quantitative evaluation) in the graft and distal nerve stumps. Vein plus muscle grafts were superior to vein and fresh muscle grafts both functionally and histologically. Functional results were similar to those found in traditional nerve grafts, but axon number was superior in the veins filled with muscle. This suggests that vein filled with muscle might serve as a grafting conduit for the repair of peripheral nerve injuries and could give better results than traditional nerve grafting.

引用

页码：247 / 251

页数：5

共 36 条

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