CHARACTERIZATION OF THE TYRAMINERGIC SYSTEM IN THE CENTRAL-NERVOUS-SYSTEM OF THE LOCUST, LOCUSTA-MIGRATORIA-MIGRATOIDES

被引：48

作者：

DOWNER, RGH ^{[1
]}

HIRIPI, L ^{[1
]}

JUHOS, S ^{[1
]}

机构：

[1] HUNGARIAN ACAD SCI,BALATON LIMNOL RES INST,H-8237 TIHANY,HUNGARY

来源：

NEUROCHEMICAL RESEARCH | 1993年 / 18卷 / 12期

关键词：

TYRAMINE; INSECT; CNS; DECARBOXYLASE; REUPTAKE; RELEASE;

D O I：

10.1007/BF00975042

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tyramine occurs in the central nervous system (CNS) of the migratory locust, Locusta migratoria migratoides. The distribution of tyramine within the CNS does not parallel that of octopamine. Tyramine is synthesised from tyrosine in the presence of tyrosine decarboxylase. A second decarboxylase in the CNS is active against 5HTP and DOPA. The locust ganglia incorporate tyramine by high- and low-affinity uptake processes that appear to be independent of dopamine and octopamine. Depolarisation of the locust ganglia by high potassium concentration results in calcium-dependent release of incorporated [H-3]tyramine.

引用

页码：1245 / 1248

页数：4

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