GROWTH-PHASE REGULATION OF PLASMID VIRULENCE GENES IN SALMONELLA

被引：55

作者：

GUINEY, DG

LIBBY, S

FANG, FC

KRAUSE, M

FIERER, J

机构：

[1] UNIV CALIF SAN DIEGO,SCH MED,DEPT MED 0640,LA JOLLA,CA 92093

[2] UNIV COLORADO,HLTH SCI CTR,DEPT MED,DENVER,CO 80262

[3] UNIV COLORADO,HLTH SCI CTR,DEPT PATHOL,DENVER,CO 80262

[4] UNIV COLORADO,HLTH SCI CTR,DEPT MICROBIOL,DENVER,CO 80262

[5] UNIV ZURICH HOSP,DEPT MED,CH-8091 ZURICH,SWITZERLAND

[6] VET AFFAIRS MED CTR,DEPT MED,LA JOLLA,CA

[7] VET AFFAIRS MED CTR,DEPT PATHOL,LA JOLLA,CA

来源：

TRENDS IN MICROBIOLOGY | 1995年 / 3卷 / 07期

关键词：

D O I：

10.1016/S0966-842X(00)88944-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Virulence genes in the genus Salmonella are regulated by growth phase and by environmental signals, which allows a sequential program of expression during infection. Conditions that promote the expression of loci required in systemic infection, including the plasmid-encoded spy genes, are the opposite of the factors that induce genes involved in the invasion of epithelial cells in the gastrointestinal tract.

引用

页码：275 / 279

页数：5

共 29 条

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