TETRAETHYLAMMONIUM CHLORIDE AS AN ANTIDOTE FOR CERTAIN INSECTICIDES IN MICE

被引：6

作者：

ANDREWS, TL

MISKUS, RP

机构：

[1] Pacific Southwest Forest and Range Experiment Station, U.S. Department of Agriculture, Berkeley

来源：

SCIENCE | 1968年 / 159卷 / 3821期

关键词：

D O I：

10.1126/science.159.3821.1367

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In tests on mice, tetraethylammonium chloride (TEAC) was superior to atropine sulfate as an antidote for some carbamate insecticides and nicotine; it did not produce the traumatic and sometimes fatal reactions caused by atropine sulfate, although injections of the two antidotes provided equal protection against lethal oral doses of the carbamates Zectran, NIA-10242, and Lannate. The effects of TEAC were not evaluated against the carbamates Sevin and Baygon because acute oral toxicity values could not be determined. Results with Matacil were inconclusive. Tetraethylammonium chloride was not an effective antidote against the organophosphate Parathion, but its use fully eliminates the effects of nicotine intoxication.

引用

页码：1367 / &