CYCLOPHILIN BINDS TO THE REGION OF CYCLOSPORINE INVOLVED IN ITS IMMUNOSUPPRESSIVE ACTIVITY

被引：167

作者：

QUESNIAUX, VFJ

SCHREIER, MH

WENGER, RM

HIESTAND, PC

HARDING, MW

VANREGENMORTEL, MHV

机构：

[1] SANDOZ LTD,PRECLIN RES,CH-4002 BASEL,SWITZERLAND

[2] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 1987年 / 17卷 / 09期

关键词：

D O I：

10.1002/eji.1830170921

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1359 / 1365

页数：7

共 38 条

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HESS, AD .

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[3] CYCLOSPORIN-A BINDING TO CALMODULIN - A POSSIBLE SITE OF ACTION ON LYMPHOCYTES-T [J].

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[4]

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[5] INDUCTION OF INTERLEUKIN-2 MESSENGER-RNA INHIBITED BY CYCLOSPORIN-A [J].

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LIN, YA ;

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PAETKAU, V .

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[6]

FREED BM, 1987, TRANSPLANT P, V19, P1223

[7] INVITRO IMMUNOSUPPRESSIVE PROPERTIES OF CYCLOSPORINE METABOLITES [J].

FREED, BM ;

ROSANO, TG ;

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TRANSPLANTATION, 1987, 43 (01) :123-127

[8] STIMULATION OF LYMPHOKINE RELEASE FROM T-LYMPHOBLASTS - REQUIREMENT FOR MESSENGER-RNA SYNTHESIS AND INHIBITION BY CYCLOSPORIN-A [J].

GRANELLIPIPERNO, A ;

INABA, K ;

STEINMAN, RM .

JOURNAL OF EXPERIMENTAL MEDICINE, 1984, 160 (06) :1792-1802

[9] CYCLOPHILIN - A SPECIFIC CYTOSOLIC BINDING-PROTEIN FOR CYCLOSPORIN-A [J].

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HARDING, MW ;

RICE, J ;

DRUGGE, RJ .

SCIENCE, 1984, 226 (4674) :544-547

[10]

HARDING MW, 1986, FASEB J, V45, P712

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