PROTEIN-BASED ARTIFICIAL RETINAS

被引：80

作者：

CHEN, ZP ^{[1
]}

BIRGE, RR ^{[1
]}

机构：

[1] BIOL COMPONENTS CORP,SYRACUSE,NY 13244

来源：

TRENDS IN BIOTECHNOLOGY | 1993年 / 11卷 / 07期

关键词：

D O I：

10.1016/0167-7799(93)90017-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Artificial retinas based on the light transducing photoelectric protein bacteriorhodopsin exhibit differential responsivity, edge enhancement and motion detection. Under appropriate conditions, these artificial receptors mimic the differential responsivity characteristic of mammalian photoreceptor cells. The use of orientated bacteriorhodopsin to generate the photoelectrical signal provides rapid responsivity, high quantum efficiency and offers the potential of directly coupling the protein response to charge-sensitive semiconductor arrays. The ability to manipulate the properties of the protein via chemical and genetic methods enhances design flexibility.

引用

页码：292 / 300

页数：9

共 17 条

[1] PHOTOPHYSICS AND MOLECULAR ELECTRONIC APPLICATIONS OF THE RHODOPSINS
BIRGE, RR
[J]. ANNUAL REVIEW OF PHYSICAL CHEMISTRY, 1990, 41 : 683 - 733
[2] BIRGE RR, 1989, MOLECULAR ELECTRONICS : BIOSENSORS AND BIOCOMPUTERS, P369
[3] BIRGE RR, 1991, P SOC PHOTO-OPT INS, V1432, P129, DOI 10.1117/12.44213
[4] BIRGE RR, 1992, IEEE COMPUT, V25, P56
[5] CHEN Z, 1990, P INT JOINT C NEUR N, V2, P803
[6] ORIENTATION OF THE BACTERIORHODOPSIN CHROMOPHORE PROBED BY POLARIZED FOURIER-TRANSFORM INFRARED DIFFERENCE SPECTROSCOPY
EARNEST, TN
ROEPE, P
BRAIMAN, MS
GILLESPIE, J
ROTHSCHILD, KJ
[J]. BIOCHEMISTRY, 1986, 25 (24) : 7793 - 7798
[7] MOLECULAR-ORIENTATION OF BACTERIORHODOPSIN WITHIN PURPLE MEMBRANE OF HALOBACTERIUM-HALOBIUM
HAYWARD, SB
GRANO, DA
GLAESER, RM
FISHER, KA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (09) : 4320 - 4324
[8] Lennie P., 1990, VISUAL PERCEPTION NE, P103
[9] MAHOWALD MA, 1991, SCI AM MAY, P76
[10] THEORY OF EDGE-DETECTION
MARR, D
HILDRETH, E
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1980, 207 (1167): : 187 - 217

← 1 2 →