SCALE-UP STRATEGIES FOR SOLID-STATE FERMENTATION SYSTEMS

Information available on scale-up strategies for solid state fermentation systems is scarce and empirical approaches have usually been used. Scale-up is further complicated by the involvement of various types of bioreactors intense heat generation and non-homogeneity in the system. The resulting fermentation plants are, consequently, labour and energy intensive and the development of well-founded scale-up criteria, such as those for submerged fermentation processes, is vital for extensive commercialization of solid state fermentation systems.