INHIBITION EFFECT OF ROSETTE FORMATION BETWEEN HUMAN LYMPHOCYTES AND SHEEP ERYTHROCYTES BY SPECIFIC HEPTAPEPTIDE ISOLATED FROM UREMIC FLUID AND ITS ANALOGS

被引：20

作者：

ABIKO, T

KUMIKAWA, M

SEKINO, H

机构：

[1] Kidney Center, Sendai Insurance Hospital Tsutsumimachi 3-16-1, Sendai

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 86卷 / 04期

关键词：

D O I：

10.1016/0006-291X(79)90209-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

One of middle molecular substances (H-His-Pro-Ala-Glu-Asn-Gly-Lys-OH) and its two analogs, in which the proline residue in position 2 was replaced by glycine and the alanine residue in position 3 was replaced by valine exert a inhibition effect on in vitro E-rosette formation. Its synthetic two analogs showed diminished biological activity compared to native heptapeptide. © 1979.

引用

页码：945 / 952

页数：8

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