A NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPIC AND CONFORMATIONAL STUDY OF 8 PSEUDO-TREHALOSES (D-GLUCOPYRANOSYL 5A-CARBA-D-GLUCOPYRANOSIDES AND (D-GLUCOPYRANOSYL-5A-CARBA-L-GLUCOPYRANOSIDES)

被引：15

作者：

BOCK, K ^{[1
]}

GUZMAN, JF ^{[1
]}

DUUS, JO ^{[1
]}

OGAWA, S ^{[1
]}

YOKOI, S ^{[1
]}

机构：

[1] KEIO UNIV,FAC SCI & TECHNOL,DEPT APPL CHEM,KOHOKU KU,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

CARBOHYDRATE RESEARCH | 1991年 / 209卷

关键词：

D O I：

10.1016/0008-6215(91)80144-C

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

N.m.r. data (H-1 and C-13) are presented for eight pseudo-trehalose derivatives in which the D-glucopyranosyl moiety is alpha or beta and the 5a-carbaglucopyranoside moiety is alpha-D, beta-D, alpha-L, or beta-L. The differences in the chemical shifts and the n.O.e. effects have been correlated with the preferred conformations estimated from empirical force-field calculations (HSEA), which have been used to calculate the average parameters over the whole energy surface. Of the four alpha-D-glucopyranosyl derivatives, only that with a 5a-carba-beta-D-glucopyranoside moiety (3) was a substrate for glucoamylase.

引用

页码：51 / 65

页数：15

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