THE FLUID CONTENT OF THE HUMAN INTERVERTEBRAL-DISK - COMPARISON BETWEEN FLUID CONTENT AND SWELLING PRESSURE PROFILES OF DISKS REMOVED AT SURGERY AND THOSE TAKEN POSTMORTEM

被引：65

作者：

JOHNSTONE, B ^{[1
]}

URBAN, JPG ^{[1
]}

ROBERTS, S ^{[1
]}

MENAGE, J ^{[1
]}

机构：

[1] UNIV OXFORD,PHYSIOL LAB,PARKS RD,OXFORD OX1 3PT,ENGLAND

来源：

SPINE | 1992年 / 17卷 / 04期

关键词：

INTERVERTEBRAL DISK; FLUID CONTENT; SWELLING PRESSURE; AUTOPSY SPECIMENS; SURGICAL SPECIMENS;

D O I：

10.1097/00007632-199204000-00006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The fluid content of the disc, which governs its mechanical response and biological behavior, varies with external load. Because load on the disc changes after death, the fluid content and swelling pressure profiles of human discs taken at autopsy were measured, and compared with discs removed during surgical procedures. In general, discs taken at surgery had a lower fluid content in the nucleus and a higher fluid content in the outer anulus than discs removed at autopsy. In discs removed at surgery, the swelling pressure of the nucleus was higher than that of the anulus, whereas in autopsy discs the swelling pressure profile was flat. These changes are thought to result from changes in load after death, and could influence the results of in vitro mechanical tests on the disc.

引用

页码：412 / 416

页数：5

共 28 条

[1]

Adams M.A., Hutton W.C., Mechanics of the Intervertebral Disc. Biology of the Intervertebral Disc, 2, pp. 39-72, (1988)

[2]

Adams P., Muir I.H., Qualitative changes with age of human lumbar disc, Ann Rheum Dis, 35, pp. 289-296, (1976)

[3]

Andersson G., Schultz A., Effects of fluid injection on mechanical properties of intervertebral disc, J Biomech, 12, pp. 453-458, (1979)

[4]

Armstrong J.R., Lumbar Disc Lesions, (1965)

[5]

Bayliss M.T., Johnstone B., O'Brien J.P., Proteoglycan synthesis in the intervertebral disc: Variation with age, region and pathology, Spine, 13, pp. 972-981, (1988)

[6]

Bayliss M.T., Urban J., Johnstone B., Holm S., A method for measuring 35S-sulphate incorporation rate in the intervertebral disc, J Orthop Res, 4, pp. 10-17, (1986)

[7]

Eyre D.R., Muir H., Quantitative analysis of types 1 and II collagen in human intervertebral disc at various ages, Biochim Biophys Acta, 492, pp. 29-42, (1977)

[8]

Goel V.K., Nishiyama K., Weinstein J.N., Liu Y.K., Mechanical properties of lumbar spinal motion segments as affected by partial disc removal, Spine, 11, pp. 1008-1012, (1986)

[9]

Hickey S., Hukins D., Effect of methods of preservation on the arrangement of collagen fibrils in connective tissue matrices: An x-ray diffraction study of annulus fibrosis, Connect Tissue Res, 6, pp. 223-226, (1979)

[10]

Hirano N., Tsuji H., Oshima H., Kitano S., Sano A., Analysis of rabbit intervertebral disc physiology based on water metabolism, Spine, 13, pp. 1291-1296, (1988)

← 1 2 3 →