STRUCTURAL EVOLUTION OF THE ANNEXIN SUPERGENE FAMILY

被引:68
作者
SMITH, PD [1 ]
MOSS, SE [1 ]
机构
[1] UNIV LONDON UNIV COLL,DEPT PHYSIOL,LONDON WC1E 6BT,ENGLAND
基金
英国惠康基金;
关键词
D O I
10.1016/0168-9525(94)90171-6
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The annexin family of calcium-binding proteins is is comprised of at least ten mammalian genes, with additional representatives in lower eukaryotes. Recent structural analyses of several annexin genes have provided insights into the relationship between exon organization and functional domains. We discuss the implications of these findings and speculate on the evolutionary origins of the annexin supergene family.
引用
收藏
页码:241 / 246
页数:6
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