COOPERATIVITY OF THE COIL-GLOBULE TRANSITION IN A HOMOPOLYMER - MICROCALORIMETRIC STUDY OF POLY(N-ISOPROPYLACRYLAMIDE)

被引：220

作者：

TIKTOPULO, EI

BYCHKOVA, VE

RICKA, J

PTITSYN, OB

机构：

[1] UNIV BERN,INST APPL PHYS,CH-3012 BERN,SWITZERLAND

[2] NCI,WSC,MATH BIOL LAB,BETHESDA,MD 20892

来源：

MACROMOLECULES | 1994年 / 27卷 / 10期

关键词：

D O I：

10.1021/ma00088a031

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The temperature-induced intramolecular coil-globule transition in poly(N-isopropylacrylamide) has been studied by microcalorimetry to investigate the cooperativity of this transition. Measurements were performed in the presence of sodium dodecyl sulfate (SDS) which prevents the polymer from aggregation both in the coil and in the globule state. It has been shown that the effective (van't Hoff) enthalpy of transition of a cooperative unit is 120 times less than the calorimetric enthalpy of a polymer molecule. This means that a coil-globule transition in this polymer is not an ''all-or-none'' process and occurs independently in cooperative units (''domains'') which are 120 times smaller than the polymer molecule and have a molecular weight about 6 x 10(4).

引用

页码：2879 / 2882

页数：4

共 24 条

[1]

ANUFRIEVA EV, 1972, DOKL AKAD NAUK SSSR+, V207, P1379

[2]

ANUFRIEVA EV, 1991, DOKL AKAD NAUK SSSR, V314, P895

[3] RETINOL-BINDING PROTEIN IS IN THE MOLTEN GLOBULE STATE AT LOW PH [J].