THE CONTRACEPTIVE POTENTIAL OF FERTILIZATION - A PHYSIOLOGICAL PERSPECTIVE

被引:23
作者
BEDFORD, JM [1 ]
机构
[1] CORNELL UNIV, COLL MED, DEPT CELL BIOL & ANAT, NEW YORK, NY 10021 USA
关键词
ACROSOME REACTION; CAPACITATION; CONTRACEPTION; CUMULUS OOPHORUS; FERTILIZATION; GAMETE FUSION; SPERM TRANSPORT;
D O I
10.1093/oxfordjournals.humrep.a138604
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Several separate events of the fertilization sequence (sperm capacitation, regulated sperm transport in the oviduct, sperm-cumulus interaction, sperm-zona binding, the acrosome reaction, zona penetration, gamete fusion) represent points at which conception might be preventable. Each is considered variously with reference to its biological significance, what is known about the mechanisms involved, the issues that remain to be resolved, and the prospects for specific inhibition.
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页码:842 / 858
页数:17
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