HL-A ANTIGENS OF HUMAN LYMPHOID CELLS IN LONG TERM TISSUE CULTURE

被引:54
作者
ROGENTINE, GN
GERBER, P
机构
[1] Immunology Branch, National Cancer Institute and Laboratory of Viral Immunology, Division of Biological Standards, National Institutes of Health, Bethesda, MD
关键词
D O I
10.1097/00007890-196907000-00004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Sixteen human lymphoid cell lines have been assayed for HL-A antigens using 29 antisera and the 51Cr release cytotoxicity technique. Ten HL-A antigens were identified on these cells. No two cell lines were identical. HL-A antigens were distinguishable from A, B, and Rh D red cell antigens by direct cytotoxicity and by absorption analyses. Antigens of four lines tested were stable for periods of 1 year and more. These cell lines offer potential for evaluation of unknown alloantisera, absorption of multispecific sera, and for studies of modification of cell surfaces under varying environmental and genetic influences in vitro. © 1969 by The Williams and Wilkins Co.
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页码:28 / +
页数:1
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