CREATINE KINASE ISOENZYMES IN SERUM OF CHILDREN WITH NEUROLOGICAL DISORDERS

被引:51
作者
CAO, A
DEVIRGIL.S
LIPPI, C
TRABALZA, N
机构
关键词
D O I
10.1016/0009-8981(69)90352-0
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
The isozymes of creatine kinase were studied by electrophoresis on cellogel strips in serum of children affected with acute encephalitis, tetanus, acute febrile seizures, cerebrospinal meningitis and of newborns affected with perinatal hypoxia. Activity of creatine kinase in serum was found to be increased in all these disorders. The enzyme is of the muscle type. It probably indicates increased permeability of the muscle or heart cell membranes to these enzymes, but it may be due also to decreased clearance of these enzymes from serum, due to a hitherto unknown process activated by disruption of the cerebral integrity. © 1968.
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页码:475 / &
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