ACUTE BLOCKING OF NALOXONE-PRECIPITATED OPIATE WITHDRAWAL SYMPTOMS BY METHOHEXITONE

被引：61

作者：

LOIMER, N

SCHMID, R

LENZ, K

PRESSLICH, O

GRUNBERGER, J

机构：

[1] MED UNIV VIENNA,INTENS CARE UNIT,VIENNA,AUSTRIA

[2] UNIV VIENNA,PSYCHIAT CLIN,PSYCHOACT DRUG ANAL LAB,A-1090 VIENNA,AUSTRIA

[3] UNIV VIENNA,PSYCHIAT CLIN,PSYCHODIAGNOST UNIT,A-1090 VIENNA,AUSTRIA

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1990年 / 157卷

关键词：

D O I：

10.1192/bjp.157.5.748

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

In a double-blind placebo-controlled trial of 18 patients, methohexitone blocked objective signs of opiate withdrawal caused by a bolus injection of naloxone. Furthermore, in continuing the naloxone therapy for 48 hours, no withdrawal signs appeared. Levels of withdrawal distress returned to normal levels within six days. This approach can be regarded as an effective and well tolerated withdrawal therapy with low drop-out rates.

引用

页码：748 / 752

页数：5

共 14 条

[1]

American Psychiatric Association, 1987, DIAGNOSTIC STAT MANU, V3rd

[2] OPIOID WITHDRAWAL AND NALTREXONE INDUCTION IN 48-72 HOURS WITH MINIMAL DROP-OUT, USING A MODIFICATION OF THE NALTREXONE-CLONIDINE TECHNIQUE [J].