NEGATIVE INOTROPIC EFFECT OF ADRENERGIC BETA-RECEPTOR BLOCKING DRUGS ON HUMAN HEART MUSCLE

被引：71

作者：

NAYLER, WG

CHIPPERFIELD, D

LOWE, TE

机构：

[1] Baker Medical Research Institute, Prahran, VIC

来源：

CARDIOVASCULAR RESEARCH | 1969年 / 3卷 / 01期

关键词：

D O I：

10.1093/cvr/3.1.30

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Authors' Synopsis: Dose-response curves obtained for the negative inotropic effect of three β-adrenergic receptor blocking compounds on human heart muscle closely resemble those obtained when dog heart muscle is used; the negative inotropic effect of Ciba 39,089-Ba on human heart muscle is significantly less than that of propranolol. The depressant effect of propranolol was not abolished by reserpine-pretreatment.

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页码：30 / +

页数：1

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