SELF-ASSEMBLY OF QBETA AND MS2-PHAGE PARTICLES - POSSIBLE FUNCTION OF INITIATION COMPLEXES

被引：29

作者：

HUNG, PP

LING, CM

OVERBY, LR

机构：

[1] Department of Molecular Biology, Abbott Laboratories, North Chicago

来源：

SCIENCE | 1969年 / 166卷 / 3913期

关键词：

D O I：

10.1126/science.166.3913.1638

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Four kinds of particles were reconstituted with RNA and protein from the genetically unrelated bacteriophages Qβ antd MS2, namely, two homologous and two heterologous, with respect to RNA and protein. However, once Qβ RNA (or MS2 RNA) reacted with a few molecuiles of either Qβ or MS2 protein to form a nucleoprotein complex (initiation comnplex), it formned a phagelike particle only with subsequent addition of the same protein.

引用

页码：1638 / &

共 19 条

[1] SUPPRESSION IN VITRO - IDENTIFICATION OF A SERINE-SRNA AS A NONSENSE SUPPRESSOR
CAPECCHI, MR
GUSSIN, GN
[J]. SCIENCE, 1965, 149 (3682) : 417 - +
[2] STRUCTURE OF SMALL VIRUSES
CRICK, FHC
WATSON, JD
[J]. NATURE, 1956, 177 (4506) : 473 - 475
[3] EGGAN K, 1969, J MOL BIOL, V39, P293
[4] IN VITRO TRANSLATION OF MULTISTRANDED RNA FROM ESCHERICHIA COLI INFECTED BY BACTERIOPHAGE F2
ENGELHARDT, DL
ROBERTSON, HD
ZINDER, ND
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 59 (03) : 972 - +
[5] SITE OF SYNTHESIS OF VIRAL RIBONUCLEIC ACID AND PHAGE ASSEMBLY IN MS2-INFECTED ESCHERICHIA COLI
GODSON, GN
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1968, 34 (01) : 149 - &
[6] ASSEMBLY IN VITRO OF SOME SMALL SPHERICAL VIRUSES HYBRID VIRUSES AND OTHER NUCLEOPROTEINS
HIEBERT, E
BANCROFT, JB
BRACKER, CE
[J]. VIROLOGY, 1968, 34 (03) : 492 - &
[7] SELFASSEMBLY OF DEFECTIVE PARTICLES OF BACTERIOPHAGE FR
HOHN, T
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1967, 2 (02): : 152 - &
[8] USE OF DEAE-CELLULOSE FOR ISOLATION OF RIBONUCLEIC ACIDS FROM BACTERIOPHAGES QBETA AND MS2
HUNG, PP
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1969, 186 (01) : 220 - &
[9] RECONSTITUTION OF INFECTIVE BACTERIOPHAGE QBETA
HUNG, PP
OVERBY, LR
[J]. BIOCHEMISTRY, 1969, 8 (03) : 820 - &
[10] HUNG PP, 1969, VIROLOGY, V38, P813

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