EFFECT OF INHOMOGENEITIES AND FINITE BOUNDARIES ON TEMPERATURE DISTRIBUTIONS IN A PERFUSED MEDIUM, WITH APPLICATION TO TUMORS

被引：19

作者：

JAIN, RK

机构：

[1] Department of Chemical Engineering and Applied Chemistry, Columbia University, New York, NY

[2] Department of Chemical Engineering, Carnegie-Mellon University, Pittsburgh, PA

来源：

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 1978年 / 100卷 / 04期

关键词：

D O I：

10.1115/1.3426216

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Analytical and numerical solutions are obtained for temperature distributions in a finite and inhomogeneous perfused medium with internal heat generation. Extensive numerical simultaUons are carried out using parameters characteristic of a solid tumor, Walker 256 carcinoma. The results obtained adequately describe the existing data on temperature distributions in tumors under two different conditions: (i) tumors under normal conditions, and (ii) tumors grown about and subsequently heated by a spherical heat source implanted in their center. © 1978 by ASME.

引用

页码：235 / 241

页数：7

共 17 条

[1]

Jain R.K., Gullino P.M., Analysis of Transient Temperature Distributions in a Perfused Medium Due to a Spherical Heat Source, with Application to Heat Transfer in Tumors: Homogeneous and Infinite Medium, A.I.Ch.E. Journal, (1978)

[2]

Gautherie M., Bourjal P., Quenneville Y., Gros C., Puissance Thermogene des Epitheliomas Mammaires I. Determination par Thermometrie Intratumorale ae Thermographic Infrarouge Cutanee, Rev. Europ. Etudes Clin, Et Biol, 17, pp. 776-781, (1972)

[3]

Jain R.K., Grantham F.H., Gullino P.M., Blood Flow and Heat Transfer in Walker 256 Mammary Carcinoma, Journal of National Cancer Institute, (1978)

[4]

Bowman H.F., Cravalho E.G., Woods M., Theory, Measurements and Application of Thermal Properties of Biomaterials, Annual Review of Biophysics and Bioenqineerinq, 4, pp. 43-80, (1975)

[5]

Chato J.C., Heat Transfer in Bioengineering, Advanced Heat Transfer, pp. 395-412, (1969)

[6]

Fan L.T., Hsu F.T., Hwang C.L., A Review of Mathematical Models of the Human Thermal System, IEEE Trans. Biomedical Engineering, 18, pp. 218-223, (1971)

[7]

Pennes H.H., Analysis of Tissue and Arterial Blood Temperatures in the Resting Human Forearm, Journal of Applied Physiology, 93, pp. 1-3, (1948)

[8]

Seagrave R.C., Biomedical Applications of Heat and Mass Transfer, (1971)

[9]

Jenson V.G., Jeffreys G.V., Mathematical Methods in Chemical Engineering, (1963)

[10]

Sien P., Jain R.K., Temperature Distributions in Normal and Neoplastic Tissues During Hyperthermia: Lumped Parameter Analysis, Journal of Thermal Biology, (1978)

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