AN IMPROVED SYNTHESIS OF PYRROLES FROM N-PARA-TOLUENESULFONYLGLYCINE ESTERS AND ALPHA,BETA-UNSATURATED ALDEHYDES AND KETONES

被引：31

作者：

LASH, TD

HOEHNER, MC

机构：

[1] Department of Chemistry, Illinois State University, Normal, Illinois

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 07期

关键词：

D O I：

10.1002/jhet.5570280705

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-p-Toluenesulfonylglycine esters 2 condensed with alpha,beta-unsaturated carbonyl compounds 1 in the presence of the non-nucleophilic base DBU to give hydroxypyrrolidines 3. Dehydration with phosphorus oxychloride-pyridine, followed by DBU mediated elimination of p-toluenesulfinic acid, gave a series of synthetically useful pyrrole-2-carboxylates 5.

引用

页码：1671 / 1676

页数：6

共 34 条

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