STABILITY OF FK-506 IN WHOLE-BLOOD SAMPLES

被引：15

作者：

FREEMAN, DJ

STAWECKI, M

HOWSON, B

机构：

[1] UNIV WESTERN ONTARIO,DEPT MED,LONDON,ON,CANADA

[2] UNIV WESTERN ONTARIO HOSP,TRANSPLANTAT LAB,LONDON,ON N6A 5A5,CANADA

来源：

THERAPEUTIC DRUG MONITORING | 1995年 / 17卷 / 03期

关键词：

TACROLIMUS; FK; 506; BLOOD ANALYSIS; STABILITY;

D O I：

10.1097/00007691-199506000-00009

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The effect of storage time and temperature on the stability of FK506 in patient blood samples and quality control samples was assessed with the Abbott IMx microparticle enzyme immunoassay. Blood FK506 concentrations measured at days 0, 2, 3, 4, 7, and 14 were stable at room (22 degrees C), refrigerator (4 degrees C), and freezer (-70 degrees C) temperatures for the 2-week study period. Patient samples stored at -70 degrees C for almost 1 year and then reanalyzed for FK506 were also found to be stable.

引用

页码：266 / 267

页数：2