EXPERIMENTAL CORTICOSTEROID MYOPATHY

被引：28

作者：

SHEAHAN, MG

VIGNOS, PJ

机构：

[1] Case Western Reserve University School of Medicine, Cleveland, Ohio

[2] Arthritis Unit, University Hospitals of Cleveland, Cleveland, Ohio

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 05期

关键词：

D O I：

10.1002/art.1780120505

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Triamcinolone treatment in rabbits using 1 mg./Kg. doses produces a differential metabolic effect, with predominant involvement of glycolytic‐type fibers of muscle manifested by a significant atrophy of type II fibers. A consequent atrophy of muscle containing a large proportion of type II fibers also occurs. These changes take place before there is any significant alteration in size of type I fibers, and before there is any apparent loss of either glycolytic or oxidative enzyme activity. Copyright © 1969 American College of Rheumatology

引用

页码：491 / &

共 21 条

[1]

BULLARD HH, 1919, HOPKINS HOSP REP, V18, P323

[2] CORTISONE MYOPATHY IN RABBITS - A LIGHT AND ELECTRON MICROSCOPIC STUDY [J].