CONJUGATE REDUCTION OF POLYFUNCTIONAL ALPHA,BETA-UNSATURATED CARBONYL-COMPOUNDS USING [(PH3P)CUH]6 - COMPATIBILITY WITH HALOGEN, SULFONATE, AND GAMMA-OXYGEN AND SULFUR SUBSTITUENTS

被引：67

作者：

KOENIG, TM ^{[1
]}

DAEUBLE, JF ^{[1
]}

BRESTENSKY, DM ^{[1
]}

STRYKER, JM ^{[1
]}

机构：

[1] INDIANA UNIV,DEPT CHEM,BLOOMINGTON,IN 47405

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)89032-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In contrast to organocuprate conjugate addition and standard methods for conjugate reduction, use of the stable copper(I) hydride cluster, [(Ph3P)CuH]6, allows chemoselective conjugate reduction of α,β-unsaturated carbonyl compounds substituted at the γ-position with leaving groups. In addition, the compatibility of the conjugate reduction with organic halides and sulfonate groups is demonstrated. © 1990.

引用

页码：3237 / 3240

页数：4

共 26 条

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