RAPID METHOD FOR THE DETECTION AND DETERMINATION OF ARTEMISININ BY GAS-CHROMATOGRAPHY

被引：46

作者：

SIPAHIMALANI, AT

FULZELE, DP

HEBLE, MR

机构：

[1] Bio-Organic Division, Plant Biotechnology Section, Bhabha Atomic Research Centre, Bombay, 400 085, Trombay

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 538卷 / 02期

关键词：

D O I：

10.1016/S0021-9673(01)88868-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Artemisinin, an antimalarial principle of Artemisia annua, is thermally unstable and decomposes on the column to give two peaks under various gas chromatographic conditions. A simple and rapid method was developed for its indirect detection and determination, at nanogram levels, both in plants and in tissue cultures developed from the plants. It is based on the linear relationship obtained between the concentration of artemisinin and the respective peak areas for either of the two thermally degraded products.

引用

页码：452 / 455

页数：4

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