POLAROGRAPHIC ANALYSIS FOR CORTICOSTEROIDS .3. DETERMINATION OF CORTICOSTEROIDS IN SINGLE-COMPONENT TABLETS

被引:21
作者
DEBOER, HS [1 ]
LANSAAT, PH [1 ]
KOOISTRA, KR [1 ]
VANOORT, WJ [1 ]
机构
[1] STATE UNIV UTRECHT,FAC PHARM,DEPT ANALYT PHARM,NL-3511 GH UTRECHT,NETHERLANDS
关键词
D O I
10.1016/S0003-2670(01)93271-4
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The differential pulse polarographic determination of Corticosteroids in single-component tablets is described. The active compounds are extracted from the excipients with a solvent with similar lipophilicity as the polarographic solvents, with a yield of about 100%. The corticosteroid esters and alcohols are determined by standard addition methods. The standard deviations range from 0.5 to 2.5% depending on the excipients and on the method of extraction. © 1979.
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页码:275 / 279
页数:5
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