STEREOSELECTIVE SYNTHESIS OF (+/-)-4-EPI-ACETOMYCIN BY THE ESTER ENOLATE CARROLL REARRANGEMENT

被引：20

作者：

ECHAVARREN, AM ^{[1
]}

DEMENDOZA, J ^{[1
]}

PRADOS, P ^{[1
]}

ZAPATA, A ^{[1
]}

机构：

[1] UNIV AUTONOMA MADRID,DEPT QUIM,E-28049 MADRID,SPAIN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 44期

关键词：

(+/-)-4-EPI-ACETOMYCIN; STEREOSELECTIVE SYNTHESIS; CARROLL REARRANGEMENT; CLAISEN REARRANGEMENT; GAMMA-BUTYROLACTONE;

D O I：

10.1016/0040-4039(91)80185-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of (+/-)-4-epi-acetomycin has been completed by the stereoselective ester enolate Carroll rearrangement of (E)-2-butenyl 2-methylacetoacetate, followed by ozonolysis and acetylation. The synthesis of (+/-)-acetomycin and its three diastereomers by a related route is also described.

引用

页码：6421 / 6424

页数：4

共 21 条

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