REGIOSELECTIVE SYNTHESIS OF HIGHLY SUBSTITUTED FURANS VIA TANTALUM ALKYNE COMPLEXES

被引：22

作者：

KATAOKA, Y ^{[1
]}

TEZUKA, M ^{[1
]}

TAKAI, K ^{[1
]}

UTIMOTO, K ^{[1
]}

机构：

[1] KYOTO UNIV,FAC ENGN,DEPT IND CHEM,YOSHIDA,KYOTO 60601,JAPAN

来源：

TETRAHEDRON | 1992年 / 48卷 / 17期

关键词：

TANTALUM; NIOBIUM; METAL ALKYNE COMPLEX; ISOCYANIDE; FURAN;

D O I：

10.1016/S0040-4020(01)88488-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of 2,3,4-trisubstituted furans are prepared by treatment of tantalum-alkyne complexes with aldehydes followed by addition of an isocyanide in DME-PhH-THF(1:1:1). The regioselectivity of the reaction depends on the bulkiness of substituents on acetylenes and the bulkier substituents tend to possess 4-position of the produced furans. 4-Trialkylsilyl-substituted furans are produced exclusively when trialkylsilylacetylenes are employed.

引用

页码：3495 / 3502

页数：8

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