EFFECT OF SITE-SPECIFIC MODIFICATION ON RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES

被引：326

作者：

MCCLELLAND, M

NELSON, M

RASCHKE, E

机构：

[1] MEGABASE RES PROD, LINCOLN, NE 68503 USA

[2] UNIV BONN, D-53115 BONN, GERMANY

来源：

NUCLEIC ACIDS RESEARCH | 1994年 / 22卷 / 17期

关键词：

D O I：

10.1093/nar/22.17.3640

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Restriction endonucleases have site-specific interactions with DNA that can often be inhibited by site-specific DNA methylation and other site-specific DNA modifications. However, such inhibition cannot generally be predicted. The empirically acquired data on these effects are tabulated for over 320 restriction endonucleases. In addition, a table of known site-specific DNA modification methyltransferases and their specificities is presented along with EMBL database accession numbers for cloned genes.

引用

页码：3640 / 3659

页数：20

共 466 条

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