1-OXA-3-CYCLOOCTYNE

被引：12

作者：

MEIER, H

STAVRIDOU, E

ROTH, S

MAYER, W

机构：

[1] Institut für Organische Chemie, Universität Mainz, Mainz, D-6500

来源：

CHEMISCHE BERICHTE | 1990年 / 123卷 / 06期

关键词：

Calculations; MNDO; Oxacyclooctynes; Ring strain; Selenadiazole fragmentation;

D O I：

10.1002/cber.19901230634

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1‐Oxa‐3‐cyclooctyne According to an MNDO calculation, 1‐oxa‐cyclooctyne (13) and 1‐oxa‐3‐cyclooctyne (14) are 8‐membered heterocyclic ring systems with high steric energy (ring strain). On the basis of THF (1) and acetoacetic ester (4), a multi‐step synthesis is described for 14. The triple bond is introduced in the last step by a thermal fragmentation of the 1,2,3‐selenadiazole 12. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：1411 / 1414

页数：4

共 13 条

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[9] STRAINED CYCLOALKENYNES
MEIER, H
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KOLSHORN, H
ZOUNTSAS, J
[J]. TETRAHEDRON, 1986, 42 (06) : 1711 - 1719
[10] MEIER H, 1986, ANGEW CHEM, V98, P838

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