EFFECT OF ALPHA-BLOCKERS AND BETA-BLOCKERS ON ETHANOL-METABOLISM

被引：5

作者：

KHANNA, JM ^{[1
]}

MAYER, J ^{[1
]}

ORREGO, H ^{[1
]}

ISRAEL, Y ^{[1
]}

机构：

[1] ADDICT RES FDN,TORONTO M5S 2S1,ONTARIO,CANADA

来源：

DRUG AND ALCOHOL DEPENDENCE | 1979年 / 4卷 / 1-2期

关键词：

D O I：

10.1016/0376-8716(79)90053-X

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

The acute administration of propranolol or phentolamine resulted in a small (16-19%) but significant reduction in the rate of ethanol disappearance in vivo in the naive Wistar rat. A reduction of essentially similar magnitude was also observed in ethanol-treated rats and pair-fed (sucrose) control animals, following the administration of these blockers. © 1979.

引用

收藏

页码：131 / 135

页数：5

相关论文

共 15 条

[1]

BERNSTEIN J, 1975, J PHARMACOL EXP THER, V192, P583

[2] INTERACTION OF PROPRANOLOL AND PHENTOLAMINE WITH ETHANOL IN RAT [J].

FRANKEL, D ;

KALANT, H ;

KHANNA, JM ;

LEBLANC, AE .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1976, 54 (04) :622-625

[3] EFFECTS OF CHRONIC INTAKE OF ETHANOL ON RATE OF ETHANOL METABOLISM [J].

HAWKINS, RD ;

KALANT, H ;

KHANNA, JM .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1966, 44 (02) :241-&

[4]

ISRAEL Y, 1975, FED PROC, V34, P2052

[5] EFFECT OF PROPRANOLOL ON ETHANOL METABOLISM-EVIDENCE FOR ROLE OF MITOCHONDRIAL NADH OXIDATION [J].

ISSELBACHER, KJ ;

CARTER, EA .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (02) :169-174

[6] EFFECT OF INHIBITORS AND INDUCERS OF DRUG METABOLISM ON ETHANOL METABOLISM IN-VIVO [J].

KHANNA, JM ;

KALANT, H .

BIOCHEMICAL PHARMACOLOGY, 1970, 19 (06) :2033-&

[7] EFFECTS OF CHRONIC INTAKE OF ETHANOL ON RATE OF ETHANOL METABOLISM .2. INFLUENCE OF SEX AND OF SCHEDULE OF ETHANOL ADMINISTRATION [J].

KHANNA, JM ;

KALANT, H ;

BUSTOS, G .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1967, 45 (05) :777-&

[8]

KHANNA JM, 1977, ALCOHOL INTOXICATI A, V3, P281

[9]

LIEBER CS, 1963, T ASSOC AM PHYSICIAN, V76, P289

[10] ALTERATION OF ETHANOL-INDUCED CHANGES IN LOCOMOTOR-ACTIVITY BY ADRENERGIC BLOCKERS IN MICE [J].

MATCHETT, JA ;

ERICKSON, CK .

PSYCHOPHARMACOLOGY, 1977, 52 (02) :201-206