COMPARATIVE-STUDY ON CYTOCHROME-P-450 OF YEASTS USING SPECIFIC ANTIBODIES TO CYTOCHROMES P-450ALK AND P-45014DM

被引：6

作者：

KAERGEL, E

AOYAMA, Y

SCHUNCK, WH

MUELLER, HG

YOSHIDA, Y

机构：

[1] NATL ACAD SCI GDR,CENT INST MOLEC BIOL,BERLIN,GERMANY

[2] MUKOGAWA WOMENS UNIV,FAC PHARMACEUT SCI,NISHINOMIYA,HYOGO 663,JAPAN

来源：

YEAST | 1990年 / 6卷 / 01期

关键词：

alkane hydroxylase; Cytochrome P‐450; Immunological Analysis; Lanosterol; 14α‐demethylase;

D O I：

10.1002/yea.320060107

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The occurrence of cytochrome P‐45014DM(lanosterol 14α‐demethylase) and cytochrome P‐450alk (long‐chain alkane terminal hydroxylase) in various yeast strain was determined with immunological procedures. Cytochrome P‐45014DM, which is a constitutive or housekeeping enzyme playing an essential role in ergosterol biogenesis, was found in all yeast strains so far tested. Cytochromes P‐45014DM from different species of yeast were immunologically different, although they may have a few common antigenic sites. In contrast, cytochrome P‐450alk was detected only in the alkane‐assimilating yeasts. Copyright © 1990 John Wiley & Sons Ltd.

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页码：61 / 67

页数：7

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