COLORECTAL-CANCER IN ULCERATIVE-COLITIS - INFLUENCE OF ANATOMICAL EXTENT AND AGE AT ONSET ON COLITIS-CANCER INTERVAL

被引：122

作者：

SUGITA, A

SACHAR, DB

BODIAN, C

RIBEIRO, MB

AUFSES, AH

GREENSTEIN, AJ

机构：

[1] CUNY MT SINAI SCH MED, MT SINAI SCH MED, DEPT SURG, DIV GASTROENTEROL, NEW YORK, NY 10029 USA

[2] CUNY MT SINAI SCH MED, MT SINAI SCH MED, DEPT BIOMATH SCI, DIV GASTROENTEROL, NEW YORK, NY 10029 USA

[3] CUNY MT SINAI SCH MED, MT SINAI SCH MED, DEPT MED, DIV GASTROENTEROL, NEW YORK, NY 10029 USA

来源：

GUT | 1991年 / 32卷 / 02期

关键词：

D O I：

10.1136/gut.32.2.167

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We have examined the age at onset of both ulcerative colitis and colitis-associated colorectal cancer in 100 patients seen at Mount Sinai Hospital between 1959 and 1988. There were 85 patients with extensive colitis and 15 with left sided colitis. There was a strong direct correlation between the age at onset of ulcerative colitis and age at diagnosis of cancer (p < 0.0001); this correlation was found both in patients with extensive colitis (p < 0.0001) and in those with left sided colitis (p < 0.005). Patients with left sided colitis developed both their colitis and their cancers about a decade later than did those with extensive disease, but the mean duration of colitis before diagnosis of cancer was virtually the same (about 21 years) in both groups, irrespective of the age at onset of disease.

引用

页码：167 / 169

页数：3

共 17 条

[1] THE RISK OF COLORECTAL-CANCER IN ULCERATIVE-COLITIS - AN EPIDEMIOLOGIC-STUDY [J].