ALTERNATIVE SPLICING OF MOUSE-BRAIN 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE MESSENGER-RNA

被引：41

作者：

KURIHARA, T

MONOH, K

SAKIMURA, K

TAKAHASHI, Y

机构：

[1] Department of Neuropharmacology, Brain Research Institute, Niigata University, Niigata

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 170卷 / 03期

关键词：

D O I：

10.1016/0006-291X(90)90502-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A second cDNA for mouse brain 2′,3′-cyclic-nucleotide 3′-phosphodiesterase (cDNAII) encoding 420 amino acids was isolated. The only difference from the cDNA obtained previously (cDNAI), which encodes 400 amino acids, was the 5′-end 53 bp. Comparison of the sequence of the mouse gene with the sequence of cDNAII indicates alternative splicing within exon 1. The 5′-end sequence of cDNAII was found in a region of the gene upstream of exon 1 and a second transcription initiation site was identified. © 1990.

引用

页码：1074 / 1081

页数：8

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