HERPES-SIMPLEX VIRUS DETECTION FROM GENITAL LESIONS - A COMPARATIVE-STUDY USING ANTIGEN-DETECTION (HERPCHEK) AND CULTURE

被引：28

作者：

CONE, RW

SWENSON, PD

HOBSON, AC

REMINGTON, M

COREY, L

机构：

[1] UNIV WASHINGTON,DEPT LAB MED,SEATTLE,WA 98195

[2] UNIV WASHINGTON,DEPT MED,SEATTLE,WA 98195

[3] SEATTLE KING CTY DEPT PUBL HLTH,SEATTLE,WA 98104

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1993年 / 31卷 / 07期

关键词：

D O I：

10.1128/JCM.31.7.1774-1776.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The sensitivity of a rapid enzyme immunoassay test (HerpChek Direct Herpes Simplex Virus Antigen Test [DuPont Medical Products, Wilmington, Del.]) for the detection of herpes simplex virus (HSV) antigens in patient specimens was compared with HSV culture. HerpChek positivity for HSV occurred with 179 (65%) of 275 lesion specimens, whereas culture for HSV was positive for 145 (53%) lesions (P = 0.002). HerpChek was twice as sensitive as culture for the detection of HSV in late-stage lesions and was equivalent to culture for the detection of HSV in early lesions. We conclude that HerpChek provides greater sensitivity than culture for HSV detection in late-stage genital lesions.

引用

页码：1774 / 1776

页数：3

共 13 条

[1] COMPARISON OF WESTERN BLOT (IMMUNOBLOT) AND GLYCOPROTEIN-G-SPECIFIC IMMUNODOT ENZYME ASSAY FOR DETECTING ANTIBODIES TO HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 IN HUMAN-SERA [J].