ADENOSINE IN PAINFUL LEGS AND MOVING TOES SYNDROME

被引：18

作者：

GUIEU, R ^{[1
]}

SAMPIERI, F ^{[1
]}

POUGET, J ^{[1
]}

GUY, B ^{[1
]}

ROCHAT, H ^{[1
]}

机构：

[1] CHU TIMONE, MALAD MUSCULARIES CLIN, MARSEILLE, FRANCE

来源：

CLINICAL NEUROPHARMACOLOGY | 1994年 / 17卷 / 05期

关键词：

PAINFUL LEGS AND MOVING TOES; ADENOSINE;

D O I：

10.1097/00002826-199410000-00009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Painful legs and moving toes is a rare syndrome with controversial physiopathology. We report two cases that were relieved by applying transcutaneous vibratory simulation. The pain relief was objectively evaluated using the nociceptive flexion reflex of the lower limb (RIII reflex). In these patients, we found a deficiency in circulating adenosine levels, which was not found in other chronic painful syndromes (sciatic pain). Based on these observations, we successfully treated patients with painful legs and moving toes by the administration of ATP. The deficit in blood adenosine may be an explanation of the physiopathology of this syndrome.

引用

页码：460 / 469

页数：10

共 35 条

[1] ANTINOCICEPTION PRODUCED BY INTERACTIONS BETWEEN INTRATHECALLY ADMINISTERED ADENOSINE AGONISTS AND NOREPINEPHRINE [J].